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Wednesday, June 3, 2009

Bladder cancer and BCG Immunotherapy




Bacillus Calmette-Guerin
First used 1921

Morales et. Al. 1976 (successful treatment in 7 of 9 patients of recurrent Ta and T1 tumours)
Live attenuated M.Bovis. (Freeze dried vaccine)

All derived from Pasteur Institute strain.
Connaught 81 mg or 180 * 10 8 CFU
Tice 12.5 mg or 2-8 *10 8 CFU
Pasteur
Frappier
Tokyo

Indications:
Mulitiple G2 pT1
G3 pTa / pT1, CIS

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